IGF1 Receptor (IGF1R) Human shRNA Plasmid Kit (Locus ID 3480)

SKU TG320384

IGF1R - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 3480
• Synonyms: CD221; IGFIR; IGFR; JTK13
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: IGF1R - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 3480). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_000875, NM_001291858, NM_000875.2, NM_000875.3, NM_000875.4, NM_001291858.1, BC113610, BC010607, BC078157, BC088377, BC107089, BC111046, BC113612, BC143721, BM264223, NM_001291858.2, NM_000875.5
• UniProt ID: P08069
• Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient